Spironolactone As A Solution For Pcos – Is It Effective?

Polycystic Ovary Syndrome, or PCOS, hits puberty-struck women in all over the world including The United States. This condition is quite common and is seen in every 1 in 10 women. PCOS is a significant obstacle for those desiring to conceive. So, if you are amongst those who are looking for ways to combat this issue, give this piece a read. We have discussed the role and effectiveness of Spironolactone for PCOS.

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    What is Spironolactone and How Does It Work for PCOS?

    While Spironolactone is not officially approved by the FDA for PCOS treatment, it is frequently prescribed “off-label” to manage the symptoms of this condition. PCOS shows up with signs like high levels of androgens (male hormones) in the body – a major cause of infertility, menstrual dysfunction, and disrupted ovulation.

    Spironolactone is a well-known diuretic prescribed for high blood pressure or swelling due to excess fluid. However, this medication shows effectiveness in various areas too. It is particularly helpful for PCOS-struck women experiencing hirsutism, an excessive growth of unwanted hair.

    Hyperandrogenism is an excess of androgen hormones. While low levels are present in women, elevated levels exacerbate symptoms, including hair loss, acne, and hirsutism.

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    How Effective Is Spironolactone for PCOS?

    Spironolactone has proven highly effective in reducing unwanted hair growth and alleviating acne in young women, especially when standard routes of treatments like oral contraceptive pills do not deliver the desired results. The majority of individuals who take Spironolactone experience positive outcomes.

    Any Side Effects?

    Most people who take Spironolactone experience minimal or no side effects, and any side effects that do occur are usually temporary and resolve when the medication is discontinued.

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    Other Uses of Spironolactone

    Spironolactone’s use extends further beyond an anti-androgen medication for PCOS. Here are some other conditions for which it can be beneficial:

    1. Hormonal Acne
      Although its use is not officially approved for acne treatment, Spironolactone is prescribed off-label to address it. This medication is an androgen blocker; thus, it reduces the influence of androgenic hormones on your skin (a common issue with women with PCOS)
      Androgens increase sebum production in your skin, making you more prone to acne breakouts. Spironolactone minimizes the impact, reducing sebum levels and the likelihood of acne.
    2. Hair Loss
      High androgen often leads to male pattern baldness. Women also experience hair loss due to the same hormones, particularly dihydrotestosterone (DHT). Spironolactone indirectly influences DHT levels by reducing testosterone production in the body, leading to a decrease in hormonal hair loss.

    Closing Note

    Spironolactone, although not FDA-approved for PCOS, has demonstrated its efficacy in treating the symptoms of this condition. It offers hope to individuals struggling with hirsutism. Do not hesitate to reach out to our expert obstetrician and gynecologist, Dr. Munira Dudhbhai, certified with the American Board of Obstetrics and Gynecology from Lewisville Women’s Care. We are just a call away to help you. Call us at (972) 956-8008 to schedule an appointment today.


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